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Exploring the Effects of Aerobic Exercise Combined with BFRT on Patients with COPD

Exploring the Effects of Aerobic Exercise Combined with BFRT on Patients with COPD

Recruiting
30-85 years
All
Phase N/A

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Overview

Investigate the effects of exercise training on the cardiopulmonary function and exercise capacity in COPD patients.

Description

The systemic effects of Chronic Obstructive Pulmonary Disease (COPD) can precipitate a series of complications, including cardiovascular disorders, muscle atrophy, and osteoporosis. These comorbid conditions often result in decreased physical activity and suboptimal physical fitness, compelling patients to lead a sedentary lifestyle to mitigate exercise-induced dyspnea. Addressing the limitations in exercise tolerance remains a critical therapeutic goal in the treatment of COPD. According to research, exercise intolerance is caused by both poor pulmonary function and associated skeletal muscle dysfunction. Blood flow restriction training, a new rehabilitation technique, has shown promise in improving muscular strength at lower exercise intensities and in shorter timeframes, presenting a fresh approach to COPD rehabilitation.

The research aims to investigate the impact of incorporating blood flow restriction training into a holistic aerobic exercise program on exercise capacity and quality of life among patients with COPD. The findings are intended to clarify the potential of this innovative training technique as a supplementary therapeutic strategy in the management of COPD.

Eligibility

Inclusion Criteria:

  1. COPD classified as levels 2-4.
  2. Stable condition without worsening in the past three months.
  3. No participation in any rehabilitation program within the past six months.
  4. Ability to understand and follow verbal commands and cooperate with an exercise training program.

Exclusion Criteria:

  1. Unconscious or unable to cooperate with the evaluator.
  2. Hospitalization due to acute illness within the past three months.
  3. Severe joint diseases or history of lower limb surgery.
  4. Severe cardiovascular disease (e.g., presence of a cardiac pacemaker or acute myocardial infarction within the past six months).
  5. Dependence on oxygen supply.

Study details
    Chronic Obstructive Pulmonary Disease

NCT06756646

National Cheng Kung University

15 October 2025

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