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Pediatric Adhesion and New Dermal Approach Study

Pediatric Adhesion and New Dermal Approach Study

Recruiting
1-17 years
All
Phase N/A

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Overview

The purpose of this study is to see if the Zio® monitor device can be worn by children for up to 14-days and to determine if the skin preparation process will provide good adherence to the skin and clear signal quality. The Zio® monitor (Study Device) is an adhesive patch that is worn on the upper left chest for a specified period of time and is similar to a band aid. The Study Device contains a battery-powered heart monitor and will look at the heart rhythm and rate.

Description

This is a prospective single-arm study to demonstrate adequate analyzable time for use in pediatric patients up to 14 days of device wear. The study will incorporate a simplified skin preparation procedure. The objective is to evaluate analyzable time of the Zio® monitor device over the wear duration (up to 14 days) in a population 1 to 17 years of age. The study will incorporate a simplified skin preparation procedure.

Eligibility

Inclusion Criteria:

  1. Child is <18 years of age and ≥1 year of age and weighing >10 kg (22 pounds) at the time of device application.
  2. Child's legally authorized representative is willing and able to provide informed consent and be able to assist the Child in completing all visits for the study. If the Child is old enough to provide assent, it will also be captured.
  3. The prescribed Zio monitor wear time is planned to be up to 14 days.

Exclusion Criteria:

  1. Child has a known allergy to adhesives or hydrogels or with family history of adhesive skin allergies.
  2. Child has a visible skin injury or broken skin at location for study device placement.
  3. Child has skin damage and a discharge of clear fluid or pus at the location for study device placement.
  4. Child is unable or unwilling to participate or comply with study protocol.
  5. The local Investigator deems the Child has a condition that could limit the Child's ability or willingness to participate in the study, or ability to comply with study required procedures and/or follow-up visits. (It is understood that younger age groups of children may present development behavioral challenges in compliance with use of medical devices. Normal development stage should not be considered a reason for exclusion).
  6. The child has experienced symptomatic episodes where instance variations in cardiac performance could result in immediate danger to the child or when real-time or in-patient monitoring should be prescribed.
  7. Child has an external or wearable cardiac defibrillator or may be exposed to high frequency surgical equipment near strong magnetic fields or devices such as MRI during the wear period.
  8. Child has a neuro-stimulator, as it may disrupt the quality of ECG data.

Study details
    Syncope
    Pediatric
    Congenital Athymia
    Congenital Heart Disease
    Arrhythmia
    Arrhythmia in Children

NCT07118124

iRhythm Technologies, Inc.

15 October 2025

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