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A Study of the Correlation Between Portal Vein Thrombosis and Prognosis of Liver Transplantation

A Study of the Correlation Between Portal Vein Thrombosis and Prognosis of Liver Transplantation

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this observational study is to investigate the correlation between portal vein thrombosis (PVT) and the prognosis of liver transplantation. The main questions it aims to address are:

What is the prevalence of PVT? What are the risk factors associated with PVT? What is the prognostic impact of preoperative PVT on liver transplantation?

Participants are divided into two groups: the PVT group and the non-PVT group. The investigators will comparatively analyze the data of both groups, estimate the prevalence and risk factors of PVT, construct a predictive model for PVT that is applicable in clinical settings, and clarify the prognostic effects of PVT.

Description

The investigators aim to investigate the prevalence and risk factors of PVT, to develop a novel grading or rating system for PVT, and to explore the prognostic impact of preoperative PVT in liver transplantation.

The investigators will:

Recruit patients according to the inclusion/exclusion criteria and obtain signed informed consents. They will collect demographic and laboratory characteristics and classify patients into the PVT group and the non-PVT group based on preoperative ultrasound and/or computed tomography.

Collect patients' perioperative medical imaging, surgical procedures, pathology reports, postoperative treatments, follow-up data, and clinical endpoints.

Comparatively analyze the data of the PVT and non-PVT groups, estimate the prevalence and risk factors of PVT, construct a predictive model for PVT that is applicable in clinical settings, clarify the prognostic effects of PVT, and propose a grading/rating system for PVT.

Eligibility

Inclusion Criteria:

  1. Liver transplantation recipients
  2. Aged 18 years or older.

Exclusion Criteria:

  1. Retransplantation
  2. Multi-organ transplantation
  3. Portal vein tumor thrombus

Study details
    Portal Vein Thrombosis

NCT06513780

Ru-zhou Cai

15 October 2025

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