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Erector Spinae Plane Block for Acute Back Pain in the Emergency Department

Erector Spinae Plane Block for Acute Back Pain in the Emergency Department

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this clinical trial is to learn if an erector spinae plane block (ESPB; a type of nerve block) works to reduce pain in adults presenting to the emergency department with low back pain. It will also learn if the ESPB reduces pain, disability, and return to work at 7 days. The main questions it aims to answer are:

  1. Does the ESPB reduce short-term pain in participants with low back pain?
  2. Does the ESPB reduce longer-term pain, reduce disability, and improve return to work and activities in participants with low back pain?

Researchers will compare ESPB to a placebo (an injection that does not involve a nerve block) to see if ESPB works to treat low back pain.

Participants will:

Receive either the ESPB or a placebo injection in the emergency department Report their pain scores for up to 120 minutes Report their pain, disability, and return to work at 7 days

Eligibility

Inclusion Criteria:

  • Adults (age ≥18 years) presenting to the emergency department with isolated low back pain present less than 6 total weeks.

Exclusion Criteria:

  • Do not speak English or Spanish as a primary language
  • Are incarcerated
  • Have a known pregnancy
  • Are allergic to amide-type local anesthetics
  • Are unable to tolerate positioning for the procedure
  • Have a critical illness precluding the ability to perform the procedure.

Study details
    Low Back Pain

NCT06745453

Rush University Medical Center

15 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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