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A Study With Central Nervous System Metastatic EGFR Mutation Positive Non-small Cell Lung Cancer

A Study With Central Nervous System Metastatic EGFR Mutation Positive Non-small Cell Lung Cancer

Recruiting
18 years and older
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

This is a descriptive observational study, in which data are collected in an epidemiological fashion and prospective. This study does not intend to intervene the current medical practice of the recruited patients.

Description

This is a descriptive observational study, in which data are collected in an EGFR mutant NSCLC. Our research plan aims to use multi-omics approaches to predict the likelihood of patients developing brain metastases, assess the prognosis of brain metastasis treatment, and identify potential biomarkers.

Eligibility

Inclusion Criteria:

  • Patients must be ≥18 years.
  • Provision of fully informed consent prior to any study specific procedures.
  • Patient with EGFR 19Del or L858R mutation diagnosed histologically or cytologically. The mutations above may exist alone or together.
  • Patients must have untreated advanced Non-Small Cell Lung Cancer (NSCLC).
  • According to the RECIST 1.1 standard, the patient must have at least one measurable lesion.

Exclusion Criteria:

  • None

Study details
    NSCLC

NCT05991193

Hunan Province Tumor Hospital

15 October 2025

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