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Clinical Assessment of Adjunctive Omega-3 Versus Vitamin D Daily Supplements on Active Periodontal Therapy With Stage II Grade B Periodontitis Patients

Clinical Assessment of Adjunctive Omega-3 Versus Vitamin D Daily Supplements on Active Periodontal Therapy With Stage II Grade B Periodontitis Patients

Recruiting
25-50 years
All
Phase N/A

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Overview

Clinical Assessment of Adjunctive Omega-3 Versus Vitamin D daily Supplements on Active Periodontal Therapy with Stage II Grade B Periodontitis Patients: A Randomized controlled clinical trial.

Description

This randomized clinical trial evaluates the effect of Omega- 3 versus Vitamin D regarding Clinical evaluation

  1. Clinical attachment loss (CAL)
  2. Probing pocket depth (PPD)
  3. Modified sulcus bleeding index (mSBI)

Eligibility

Inclusion Criteria:

  • • Systemic healthy patients
    • Patients aged > 25 years
    • Patients suffering from stage II periodontitis with grade B were included in this study, according to 2017 world workshop classification of periodontal disease (Papapanou et al. 2017).
    • Patients with interdental clinical attachment loss (CAL) of 3-4 mm
    • No history of previous periodontal therapy.
    • No taken medications known to interfere healing or periodontal tissue health such as anticonvulsants, calcium channel blockers, or immunosuppressant drugs.
    • No previous periodontal surgery at involved sites.
    • Good oral hygiene and good compliance with the plaque control instructions following initial therapy.
    • Neither taken antibiotics within the last three months nor nonsteroidal anti-inflammatory drugs within the last three months
    • Absence of diseases or conditions that would interfere with wound healing such as diabetes mellitus or coagulation disorders
    • Absence of oral mucosal inflammatory conditions such as aphthous ulcers or lichen planus.

Exclusion Criteria:

  • • Patients taking Omega- 3 or Vitamin D as a nutritional supplement were excluded from the study
    • Smoking habits
    • Pregnant and lactating mothers
    • Patients who have been received periodontal surgery in the study area during the last 6 months.

Study details
    Vitamin D Deficiency

NCT06654063

Cairo University

21 October 2025

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