Overview

The goal of this observational study is to learn about the Effects of neoadjuvant therapy with carboplatin, paclitaxel combined with anti-PD-1 drugs on pain, anxiety and depression in patients with operable head and neck squamous cell carcinoma: a prospective cohort study

Eligibility

Inclusion Criteria:

• 1: Clinical diagnosis of head and neck squamous cell carcinoma (stage I-IVA), without prior treatment, and planning to undergo either surgical treatment alone or surgical treatment combined with chemotherapy and immunotherapy.2: Ability to speak Chinese and possess basic reading and writing skills.

Exclusion Criteria:

• 1: Presence of mental illnesses such as dementia or delirium. 2: Active use of narcotic drugs, including consuming alcohol more than 4 times per day or more than 4 times per week. 3: Patients who alter their treatment plan during the course of treatment. 4: Current or prior use of antidepressants.