Overview
To develop and validate a urine drug screen to detect thebaine.
Eligibility
Inclusion Criteria:
- Male or female
- Ages 18-65
- Healthy
Exclusion Criteria:
- Allergy to poppy seeds, or any of the related food stuffs used in the study
- Celiac disease or gluten sensitivity
- Ongoing or opioid use in the past 6 months
- History of renal or hepatic disease or dysfunction
- Inability or unwillingness to give repeated urine specimens
- Unwillingness to refrain from eating poppy seed-containing products during the two-day course of the study
- Non-English speakers (due to study materials being in English)
- BMI greater than 30
- Antibiotic use in the previous 2 months
- Recent ingestion of poppy seeds from the previous 7 days