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Palliative Care Protocol for Adult Patients Hospitalized in Critical Care Units.

Palliative Care Protocol for Adult Patients Hospitalized in Critical Care Units.

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this clinical trial is to determine the effectiveness of a palliative care protocol in improving the quality of care of adult patients at high risk of dying hospitalized in the critical care unit.

Assessing symptom burden (dyspnea, pain and/or anxiety/agitation) until death or day 5 (whichever comes first)

Researchers will compare the impact of the palliative care protocol with standard care to see if it improves the quality of care.

Participants will:

  1. Symptom management.
  2. Respect for the autonomy of the patient and his/her family environment.
  3. Respectful management of clinical information.
  4. Provision of holistic care and support.

Description

We designed a stepped wedge cluster randomized trial The study is implementation in 5 Chilean hospitals, admitting 248 patients.

Pre-intervention (control): The practices of each ICU will be maintained, until the moment that according to randomization corresponds the beginning of the intervention, in each center.

Post-intervention: Palliative care protocol to improve the quality of care

Eligibility

Inclusion Criteria:

  • 18 years old and older
  • Hospitalization in critical care unit for more than 48 hrs.
  • Medical indication of therapeutic effort limitation, defined as: a) Non-initiation or withdrawal of life support therapies: invasive mechanical ventilation, vasoactive drugs, cardiopulmonary resuscitation, renal replacement therapy.

Exclusion Criteria:

  • Severe communication disorder and cultural language limitation (language other than Spanish).
  • Absence of legal representative and/or caregiver.
  • Brain dead patient.

Study details
    End of Life Care
    Critical Illness
    Palliative Care

NCT06483958

University of Chile

15 October 2025

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