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Cognitive Intervention With Go and Chess in Early and Subjective Cognitive Decline

Cognitive Intervention With Go and Chess in Early and Subjective Cognitive Decline

Recruiting
55 years and older
All
Phase N/A

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Overview

The goal of this clinical trial]is to evaluate if learning to play traditional board games could improve cognition in subjects with mild cognitive impairment and subjective cognitive decline. The main questions it aims to answer are:

  • Do Go and Chess improve cognition?
  • Is a game better than the other? Is the effect of both games on cognition synergistic?
  • Do Go and Chess improve quality of life?
  • Do Go and Chess improve mood?
  • Do Go and Chess improve lifestyle?

Participants will be randomized to one of four groups:

  • Group intervention with Go, once a week, for 12 weeks
  • Group intervention with Chess, once a week, for 12 weeks
  • Group intervention with Go and Chess, twice a week, for 12 weeks
  • Control group

Eligibility

Inclusion Criteria:

  • Diagnosis of mild cognitive impairment or subjective cognitive decline
  • Willingness to participate in the board games classes
  • Living within 20-minute driving distance from the center
  • Signed informed consent

Exclusion Criteria:

  • Prior knowledge of the the game rules (in case the subject knows one of the two, they can be randomized to the other one)
  • Significant linguistic or sensory impairment (according to clinical judgment)
  • Significant behavioral or psychiatric disturbances (according to clinical judgment)
  • Significant medical comorbidities (according to clinical judgment)

Study details
    Mild Cognitive Impairment
    Subjective Cognitive Decline

NCT06281652

University of Milano Bicocca

21 October 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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