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Weight Loss Through Mayo Clinic Diet

Weight Loss Through Mayo Clinic Diet

Recruiting
18-64 years
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

The purpose of study is to evaluate the efficacy of the Mayo Clinic Diet in clinically significant weight loss (>5%) versus usual care. We also wish to evaluate the feasibility, barriers to completion, and sustainability of this intervention at the 24, and 52-week marks. Lastly, we aim to study the change in participants body composition and quality of life at the end of this intervention.

Eligibility

Inclusion Criteria:

  • Males and females (non-pregnant) 18-64
  • BMI > or = to 25 kg/m2
  • Ability to read and understand English. (as the Mayo Clinic Diet book and app are only available in English)

Exclusion Criteria:

  • Have a current diagnosis of melanoma or cancer diagnosis
  • Currently breastfeeding
  • Pregnant, or planned to be pregnant within 6 months
  • Have a diagnosis of Type 1 or 2 Diabetes Mellitus
  • Had weight loss surgery within the last year
  • Currently participating in another lifestyle weight loss program or taking medications for weight loss
  • Have lost 5% or more of their weight in the last six months
  • Have a history of eating disorders
  • Have planned surgery in the next 6 months.

Study details
    Obesity

NCT06862375

Mayo Clinic

15 October 2025

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