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Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder

Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder

Recruiting
18 years and older
All
Phase N/A

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Overview

The purpose of this clinical trial is learn whether a behavioral (non-medication) treatment can reduce nightmares in adults with Rapid Eye Movement (REM) Sleep Behavior Disorder (RBD). People with RBD will be enrolled in the study along with their romantic partners. All participants will receive the treatment via videoconference and will complete 2 assessments. Participants with RBD will attend 7 sessions, and their partners will attend 2 of those sessions with them.

Eligibility

Inclusion Criteria:

  • Diagnosis of isolated RBD or RBD secondary to neurodegenerative disease
  • Age 18 or older
  • Speak, read, and write English
  • Live in the United States
  • Nightmare frequency ≥3 times per week
  • Disturbing Dream and Nightmare Severity Index score indicative of nightmare disorder
  • Sleep, neurological, and psychiatric medications stable for at least 1 month and willing to keep medications stable through the course of the study
  • Live with a romantic partner who is willing to participate in the study

Exclusion Criteria:

  • Possible dementia
  • Narcolepsy
  • Posttraumatic stress disorder
  • Previous behavioral treatment for nightmares
  • Currently engaged in sleep- or trauma-focused psychotherapy
  • Taking a medication that could cause RBD, if the medication was started prior to onset of RBD symptoms

Inclusion Criteria (Partners):

  • Live with a romantic partner who meets all of the above criteria
  • Age 18 or older
  • Speak, read, and write English
  • Live in the United States

Study details
    Nightmare
    Nightmare Disorder With Associated Other Sleep Disorder
    REM Sleep Behavior Disorder

NCT06441864

University of Utah

15 October 2025

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FAQs

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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