Overview
Emergence delirium is a common complication in pediatrics undergoing neurosurgery. Previous study showed that a single bolus of remimazolam was associated with lower incidence of postoperative agitation. Present study was designed to investigate if remimazolam supplemented to sevoflurane anesthesia could decrease the risk of emergence delirium in pediatrics undergoing neurosurgery.
Eligibility
Inclusion Criteria:
- Aged 1 to 6 years old
- Planned to receive elective neurosurgery under general anesthesia
- Expected duration of surgery > 1 hour
Exclusion Criteria:
- Allergy to benzodiazepine
- Use of other sedatives within 12 hours before surgery such as benzodiazepines, propofol, chloral hydrate, etc.,
- ASA classification IV or above
- Unable to complete emergence delirium assessment, such as language, hearing or vision impairment.