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Effects of Nutritional Supplementation of Leucine and Polyunsaturated Fatty Acids on Muscle Health in the Elderly

Effects of Nutritional Supplementation of Leucine and Polyunsaturated Fatty Acids on Muscle Health in the Elderly

Recruiting
50-99 years
All
Phase N/A
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Overview

Population aging has become a significant global concern, and Taiwan is set to officially enter the "super-aged society" in 2025. As individuals age, various physiological functions gradually decline, including a reduction in muscle mass, which is a key aspect of the aging process.

This interventional study aims to investigate the effects of leucine-rich protein combined with polyunsaturated fatty acid supplementation on middle-aged and elderly individuals (aged 50 and above) who are at high risk for sarcopenia.

Eligibility

Inclusion Criteria:

  • Age ≥ 50 years
  • ASMI < 7 kg/m2 in men
  • ASMI < 5.7 kg/m2 in women
  • Grip strength < 28 kg in men
  • Grip strength < 18 kg in women
  • Walk speed < 1 m/s

Exclusion Criteria:

  • People who are allergic to supplements
  • cancer
  • heart failure
  • kidney disease
  • autoimmune disease
  • neurodegenerative disease

Study details
    Sarcopenia
    Sarcopenia in Elderly

NCT06991855

Chang Gung Memorial Hospital

15 October 2025

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