Overview

This research will enhance our knowledge and understanding of Cerebrospinal Fluid (CSF) circulation around the Central Nervous System (CNS) (brain and spinal cord).

The main objective is to obtain flow velocities using Phase Contrast (PC) MRI over the entire subarachnoid space (SAS). This will enable us to develop and validate a numerical model of the SAS.

Eligibility

Inclusion Criteria:

• Age ≥ 18 years at the time of agreement
• Free subject, without guardianship or curatorship or subordination
• Patients benefiting from a Social Security scheme or benefiting from it through a third party
• Informed consent signed by the patient after clear and complete information about the study

Exclusion Criteria:

• 3T MRI contraindications (pacemaker, cochlear implant, metallic splinter, etc)
• History of neurological pathology
• Previous operations involving the central nervous system (spinal surgery, neurological surgery, etc.)
• Current pathology or treatment that may interfere with the CSF or subarachnoid spaces (CSF dysregulation, disc herniation, hydrocephalus, Chiari malformation, etc.)
• Concurrent participation in another clinical research study
• Persons not covered by Social Security or not covered by Social Security through a third party
• Persons benefiting from enhanced protection, namely minors, persons deprived of their liberty by a judicial or administrative decision, adults under legal protection
• Pregnant or breastfeeding women, women of childbearing age who do not have effective contraception (hormonal/mechanical: oral, injectable, transcutaneous, implantable, intrauterine device, or surgical: tubal ligation, hysterectomy, total oophorectomy)

Exclusion criteria during the study:

• Discovery of a contraindication to 3T MRI (pacemaker, cochlear implant, metallic splinter, etc)