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Comparison of Ultrasound-Guided Serratus Combination Plane Blocks and Local Wound Infiltration for Postoperative Analgesia Management in Minimally Invasive Cardiac Surgery (MICS)

Comparison of Ultrasound-Guided Serratus Combination Plane Blocks and Local Wound Infiltration for Postoperative Analgesia Management in Minimally Invasive Cardiac Surgery (MICS)

Recruiting
18-75 years
All
Phase N/A

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Overview

This randomized, prospective, single-blinded study aims to compare the efficacy of ultrasound-guided serratus anterior plane (SAP) block combined with serratus-intercostal interfascial plane (SIP) block versus local wound infiltration (LWI) for postoperative analgesia in patients undergoing minimally invasive cardiac surgery (MICS). The primary outcome is total perioperative and postoperative opioid consumption. Secondary outcomes include postoperative pain scores (NRS), opioid-related side effects, block-related complications, and ICU stay duration.

Description

Minimally invasive cardiac surgery (MICS) has gained popularity due to reduced surgical trauma and faster recovery. However, postoperative pain management remains a challenge. This study evaluates the analgesic effectiveness of combining two interfascial plane blocks-SAP and SIP-under ultrasound guidance, compared to traditional local wound infiltration. A total of 60 patients scheduled for MICS with cardiopulmonary bypass will be randomized into two groups (SAP+SIP vs LWI). Pain scores, opioid usage, and complications will be recorded at predetermined intervals up to 72 hours postoperatively.

Eligibility

Inclusion Criteria:

  • Age 18-75 years
  • Undergoing MICS with left-sided 4th-5th intercostal incision
  • ASA I-III
  • Informed consent provided

Exclusion Criteria:

  • Coagulopathy or on anticoagulants
    • Allergy to local anesthetics or opioids
    • Local infection at block site
    • Pregnancy or lactation
    • Bilateral thoracic incisions
    • Refusal to participate

Study details
    Pain
    Postoperative
    Heart Surgery
    Analgesia

NCT06968065

İstanbul Yeni Yüzyıl Üniversitesi

21 October 2025

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