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The Role of POLE Mutation in High Risk Endometrial Cancer.

The Role of POLE Mutation in High Risk Endometrial Cancer.

Recruiting
Female
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

The actual role of POLE mutations in high-risk endometrial cancer is undetermined. The main question it aims to answer is:

What is the prevalence of POLE mutations in high-risk endometrial cancer case? What is the impact of POLE mutations in real world high-risk endometrial cancer case?

Description

All high-risk recurrent endometrial cancer cases who were treated in a tertiary referral center will be analyzed and subjected to POLE mutation analysis. In addition, survival analysis will be used to analyze the role of POLE mutations in women with high-risk endometrial cancer. We can answers the following.

  1. What is the prevalence of POLE mutations in women with high-risk endometrial cancer?
  2. What is the role of POLE mutations in real world high-risk endometrial cancer?

Eligibility

Inclusion Criteria:

  • women with high-risk for recurrent endometrial cancer

Exclusion Criteria:

  • Nil

Study details
    Endometrial Neoplasms

NCT07114653

Far Eastern Memorial Hospital

15 October 2025

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