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Trial of Latex Vs Non-latex Hemorrhoid Banding

Trial of Latex Vs Non-latex Hemorrhoid Banding

Recruiting
18 years and older
All
Phase N/A

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Overview

This study will involve the recruitment of adult patients with hemorrhoids for whom rubber band ligation is the recommended treatment. Patients will be randomized to receive banding with a latex band or non-latex band. Our goal will be to measure the performance of latex bands vs non-latex bands.

Description

This study will involve the recruitment of adult patients with symptomatic grade 2-3 internal hemorrhoids for whom rubber band ligation is the recommended treatment. Patients will be randomized to receive banding with a latex band or non-latex band. Our hypothesis is that non-latex hemorrhoidal bands are non-inferior to latex bands for the treatment of grade 2-3 internal hemorrhoids.

The secondary objective of the study is to compare banding-related adverse effects including pain, bleeding, and complications assessed both immediately and within 3 weeks following each hemorrhoidal banding.

Eligibility

Inclusion Criteria:

  • Symptomatic grade 2-3 internal hemorrhoids undergoing rubber band ligation

Exclusion Criteria:

  • Previous hemorrhoidal banding within the past year
  • Known latex allergy
  • Pregnancy
  • Anticoagulation use
  • Bleeding disorder
  • Portal hypertension
  • Inflammatory bowel disease
  • Immunosuppression
  • Functional neurologic disorder
  • Pelvic floor dysfunction
  • Any records flagged "break the glass" or "research opt out".

Study details
    Hemorrhoid
    Hemorrhoid Bleeding

NCT06625138

Huntington Memorial Hospital

15 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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