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Redirecting Immune, Lipid and Metabolic Drivers of Early Cardiovascular Disease: The RESET Cohort Study

Redirecting Immune, Lipid and Metabolic Drivers of Early Cardiovascular Disease: The RESET Cohort Study

Recruiting
40-70 years
All
Phase N/A
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  • Simplified (AI rewritten)

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Overview

Project RESET is a Singapore National Medical Research Council Large Collaborative Grant funded program that brings together a nationwide community of cardiovascular, metabolic, and digital health researchers, as well as clinicians across primary and tertiary care to study the immune, lipid and metabolic drivers of early cardiovascular disease. RESET incorporates a nested randomised controlled trials (RCT) to test the use of a combined digital wearable and AI-human symbiotic lifestyle intervention to halt or reverse the progression of early disease.

Eligibility

Inclusion Criteria:

  • 40-70 years old
  • ASCVD (atherosclerotic cardiovascular disease) score of 5% and higher

Exclusion Criteria:

  • Previous major cardiovascular disease (myocardial infarction, heart failure, ischemic stroke)
  • Limited life expectancy
  • Other ongoing unstable medical conditions
  • Pregnant women

Study details
    Cardiovascular Diseases
    Metabolic Syndrome
    Non-Alcoholic Fatty Liver Disease

NCT06211868

National University Hospital, Singapore

15 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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