Overview

The objective of this study is to evaluate whether the TCI604 probiotics has the potential to enhance human gut function and alleviate constipation.

Eligibility

Inclusion Criteria:

• Male or non-pregnant female subjects aged 18 to 65 who are willing to sign the informed consent form;
• Diagnosed with functional constipation as assessed by a physician;
• Non-pregnant females who agree to use physical contraceptive methods during the study period (e.g., condoms, intrauterine devices);
• No history of organ transplantation, epilepsy or seizures, liver or kidney disease, malignancy, psychiatric disorders, alcohol or drug abuse, or other major organic diseases (as determined by medical history).

Exclusion Criteria:

• Use of probiotics, gastrointestinal health supplements, medications, or antibiotics within 30 days prior to the study;
• Presence of chronic gastrointestinal diseases (e.g., irritable bowel syndrome [IBS], inflammatory bowel disease [IBD], Crohn's disease, celiac disease, bowel control problems/fecal incontinence, pancreatitis, peptic ulcers, colorectal cancer, short bowel syndrome, ulcerative colitis);
• History of gastrointestinal or major surgery;
• Lactose intolerance;
• Chronic diarrhea;
• Pregnant or breastfeeding women;
• Known allergy to any components of the study product.