Overview
This study investigates the correlation between ocular biological characteristics and overall conditions before and after liver transplantation by collecting ocular biological characteristics. Explore whether it is possible to construct a clinical prediction model for liver transplantation by incorporating ocular biometric features, in order to optimize disease management before and after liver transplantation.
Description
This study is a bidirectional cohort study, which retrospectively analysed data from a prospective database to construct a model, and prospectively collected patient information from preoperative to postoperative for model improvement and validation.
Eligibility
Inclusion Criteria:
- Age greater than or equal to 18 years old;
- Late stage liver disease patients waiting for liver transplantation treatment, as well as patients with varying degrees of cirrhosis;
- Can collect complete basic demographic information, liver function blood test indicators, liver pathology and imaging examination results;
- Can cooperate with eye OCT, OCTA and other examinations, and obtain qualified examination parameters;
- Voluntarily follow the clinical trial protocol and sign the informed consent form.
Exclusion Criteria:
- History of other organ transplant surgeries;
- History of intraocular laser treatment, medication injection, and surgery;
- History of high myopia, glaucoma, and retinal choroidal related eye diseases;
- History of major systemic diseases other than liver disease;
- Individuals whose overall body and eye conditions cannot cooperate with eye examinations.