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Effects of Different Anesthesia Machine Modalities on Bariatric Surgery Patients: a Prospective Randomized Controlled Study

Effects of Different Anesthesia Machine Modalities on Bariatric Surgery Patients: a Prospective Randomized Controlled Study

Recruiting
16-65 years
All
Phase N/A

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Overview

The goal of this clinical trial is to explore the clinical significance and value of the PRVC ventilation mode in Bariatric Surgery Patients. The main questions it aims to answer are:

  • Do different ventilation patterns affect intracranial pressure and partial pressure of carbon dioxide in bariatric surgery patients?
  • Does PRVC mode reduce intracranial pressure and partial pressure of carbon dioxide in bariatric surgery patients?
  • Whether intracranial pressure can be quickly measured by monitoring a patient's optic nerve sheath diameter (ONSD)? Researchers randomized bariatric surgery patients into PC, VC, and PRVC groups for comparison, looking at breathing mechanics, PaCO2, and ICP.

Participants will:

  • take PC mode ventilation, VC mode ventilation, and PRVC mode ventilation
  • monitor Respiratory mechanics, PaCO2, and ONSD

Eligibility

Inclusion Criteria:

  • Patients scheduled for elective bariatric surgery.
  • Age between 16 and 65 years.
  • Continuous weight gain for more than 5 years with a BMI ≥ 35.
  • ASA-PS (American Society of Anesthesiologists Physical Status) categorization of Grade II or III.

Exclusion Criteria:

  • Patients who were dependent on alcohol or opioids.
  • Patients with severe mental or intellectual disabilities.
  • Patients with severe ocular conditions, such as ocular trauma, optic nerve tumors, or those wearing ocular prostheses.

Study details
    Ventilation
    Bariatric Surgery
    Intracranial Pressure
    Carbon Dioxide

NCT06547411

Yu-Long Jia

21 October 2025

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