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Endotypic Stability in CRS

Endotypic Stability in CRS

Recruiting
18 years and older
All
Phase N/A
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Overview

A Case control study with 150 cases and 50 controls will be conducted. Immunologic (cytokines measurements in nasal secretions and sinonasal tissues), histopathologic (tissue eosinophilia) and clinical parameters (Lund-Mackay and Lund-Kennedy score, lung function tests), surveys (SNOT- 22, SF-36 quality of life survey) will be compared between different groups of patients

Eligibility

Inclusion Criteria:

  • Patients with Chronic sinusitis (with or without polyps)
  • Undergoing endoscopic sinus surgery during the study period
  • More than 18 years
  • No chronic illness/ malignancy

Study details
    Chronic Sinusitis

NCT06272123

Thomas Jefferson University

15 October 2025

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