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Boosting CPAP Use in Adults With Severe Sleep Apnea: Role of Motivation and Psychological Factors

Boosting CPAP Use in Adults With Severe Sleep Apnea: Role of Motivation and Psychological Factors

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this randomized prospective clinical trial is to examine whether phenotypic traits, psychological characteristics, assessed by STAI (engl. The State-Trait Anxiety Inventory) and IPIP50S (engl. International Personality Item Pool) questionnaires, and patients' self-efficacy, assessed by SEMSA (engl. Self-Eficacy Measure for Sleep Apnea) questionnaire, are associated with CPAP adherence after three months of use. The study also evaluates whether a motivational phone call one month after therapy initiation improves CPAP adherence at the three-month follow-up. The main questions it aims to answer are:

  • Are phenotypic and psychological traits associated with adherence to CPAP therapy after 3 months of treatment?
  • Can a single motivational telephone intervention, one month after initiating CPAP therapy, significantly improve CPAP adherence at the three-month follow-up compared to no intervention? Researchers will compare patients who receive a phone call to those who do not, to see if this simple intervention leads to better CPAP adherence after three months of use.

Participants will:

  • Undergo polysomnography before starting CPAP therapy,
  • Complete three questionnaires (IPIP50S, STAI, SEMSA) before starting CPAP therapy,
  • Be randomly assigned to either receive a motivational phone call one month after starting CPAP therapy or to a control group without any phone call,
  • Be invited for a follow-up after three months of CPAP use to download and analyze CPAP adherence data from their CPAP devices.

Eligibility

Inclusion Criteria:

  • Participants aged 18 years or older
  • Diagnosis of severe obstructive sleep apnea (OSA), defined as AHI ≥30
  • Signed informed consent for participation in the study
  • Adequate physical and psychological capacity to participate in the intervention and complete questionnaires
  • Patients who are initiating CPAP therapy at the Sleep Medicine Center, University of Split School of Medicine
  • Availability for follow-up over a three-month period

Exclusion Criteria:

  • Presence of central sleep apnea or other primary sleep disorders
  • Cognitive impairment or psychiatric conditions that may hinder the ability to follow instructions or complete questionnaires
  • Previous experience with CPAP therapy prior to study enrollment
  • Significant comorbidities (e.g. unstable cardiovascular disease, advanced pulmonary disease) that may interfere with study outcomes
  • Pregnancy
  • Inability to participate in follow-up assessments or be contacted by telephone

Study details
    Obstructive Sleep Apnea (OSA)

NCT06994247

University of Split, School of Medicine

15 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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