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Transversalis Fascia Plane Block Versus Intrathecal Dexmedetomidine in Patients Undergoing Cesarean Section

Transversalis Fascia Plane Block Versus Intrathecal Dexmedetomidine in Patients Undergoing Cesarean Section

Recruiting
18-40 years
Female
Phase N/A

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Overview

This study aims to compare the analgesic efficacy of the transversalis fascia plane (TFP) block and intrathecal dexmedetomidine in patients undergoing cesarean section (CS).

Description

Cesarean section (CS) is a commonly performed major surgical procedure that results in substantial postoperative pain and patient dissatisfaction.

Spinal anesthesia is commonly used in CS surgery. However, it may be associated with several side effects, particularly hypotension.

Dexmedetomidine is an α2 adrenergic receptor agonist that has an analgesic effect.

Ultrasound-guided interfascial plane blocks are often used in multimodal analgesia regimens. Local anaesthetic injection into the transversalis fascia plane (TFP) anesthetizes the proximal branches of T12 and L1 which targeted in the plane between the transversus abdominis muscle and the transversalis fascia.

Eligibility

Inclusion Criteria:

  • Age from 18 to 40 years.
  • American Society of Anesthesiology (ASA) physical status II.
  • Women undergoing cesarean section under spinal anesthesia.

Exclusion Criteria:

  • Contraindication to spinal anesthesia.
  • Women with body mass index >40 kg/m2.
  • Pregnancy-induced hypertension
  • Local infection at the site of injection.
  • Known cardiovascular disease
  • Coagulation abnormality.
  • History of chronic pain.
  • Abuse of drugs or alcohol.
  • History of allergies to any study medications.
  • Seizure disorders.
  • Any pregnancy complications requiring conversion to general anesthesia.

Study details
    Transversalis Fascia Plane Block
    Intrathecal Dexmedetomidine
    Cesarean Section

NCT07170267

Tanta University

15 October 2025

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