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Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure

Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure

Recruiting
18-40 years
Female
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

Assessing whether Preimplantation Genetic Testing for Aneuploidy (PGT-A) can increase the ongoing pregnancy rate per transferred embryo and can decrease the time to pregnancy and miscarriage rate in patients with Recurrent Implantation Failure (RIF)

Eligibility

Inclusion Criteria:

  • Women with recurrent implantation failure (previous transfer of least 4 good quality embryos in at least 3 fresh or frozen cycles)
  • BMI < 35
  • Normal hysteroscopy

Exclusion Criteria:

  • thin endometrium in previous cycles (<6mm), endometriosis ASRM score III-IV, premature ovarian failure (POF, Bologna criteria), abnormal karyotype, donor oocytes or embryos, PGT-M

Study details
    Recurrent Implantation Failure

NCT03900780

Universitaire Ziekenhuizen KU Leuven

15 October 2025

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