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Arrhythmias Detection in a Real World Population

Arrhythmias Detection in a Real World Population

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Phase N/A

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Overview

The study is a prospective multicenter registry. Consecutive patients with indications of implant / replacement or upgrade of implantable cardioverter defibrillator (ICD) will be enrolled.

The primary objective of the study is to determine the predictors of appropriate anti-tachycardia therapy (with shock) in a non-selected population of patients implanted with an ICD.

Secondary objectives of the study are:

  • the incidence of anti-tachycardia therapies;
  • the predictors of inappropriate therapy and onset of arrhythmia burden;
  • the adherence to the current guidelines in the Italian clinical practice;
  • the predictors of heart failure (HF) onset and response to cardiac resynchronization therapy (CRT).

Eligibility

Inclusion Criteria:

  • Patient implanted with a Subcutaneous (S)- Ventricular Chamber (VR)- Dual Chamber (DR) - or Cardiac Resynchronization Therapy (CRT) Defibrillator (this study will utilize all the market released CRT-D or VR/DR-ICD systems and leads)
  • Patient is willing and able to sign an authorization to use and disclose health information or an Informed Consent
  • Patient must be able to attend all required follow-up visits at the study center for at least 12 months

Exclusion Criteria:

  • Patient is participating in another clinical study that may have an impact on the study endpoints
  • Women who are pregnant or plan to become pregnant

Study details
    Appropriate and Inappropriate Shock Therapy With ICD
    Arrhythmias Detection

NCT02275637

Fondazione IRCCS Policlinico San Matteo di Pavia

15 October 2025

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