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ESP Versus PIFB for Analgesia in Open Cardiac Surgery: a Randomized Control Trial

ESP Versus PIFB for Analgesia in Open Cardiac Surgery: a Randomized Control Trial

Recruiting
18 years and older
All
Phase N/A

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Overview

This clinical trial compares analgesia efficiency and recovery outcomes between two different fascial plane block techniques (ESPB vs.PIFB) in cardiac surgery patients participant population/health conditions].

The main questions it aims to answer are:

  • Does ESPB provide superior analgesia than PIFB
  • Do patients who receive ESPB have better recovery outcomes

Description

Regional nerve blocks, including Pecto-intercostal block (PIFB) and Erector spinae plane block (ESPB), can provide a certain level of analgesia for thoracic and cardiac surgeries. This study focuses on patients undergoing their first conventional sternotomy for cardiac surgery. They are randomly assigned to receive either PIFB or ESPB for pain relief. Comparisons are made between the two groups for postoperative 48-hour analgesic medication requirements, static and dynamic postoperative pain scores, improvements in postoperative respiratory function, quality of life index (QoL15), and other clinically relevant prognostic indicators.

Eligibility

Inclusion Criteria:

  • Adults patients, elective and first-time cardiac surgery patients undergoing traditional sternotomy. Procedures include coronary artery bypass surgery, valve repair or replacement surgery, atrial and ventricular septal defect repair surgery, and other open-heart surgeries.

Exclusion Criteria:

  • 1. Emergency surgery 2. Anticipated combined major aortic vascular surgery 3. Already admitted to the ICU or on a ventilator before surgery.

Study details
    Analgesia

NCT06322810

Taichung Veterans General Hospital

15 October 2025

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