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Deprescribing in Patients Living With Dementia With Caregiver and Provider Nudges

Deprescribing in Patients Living With Dementia With Caregiver and Provider Nudges

Non Recruiting
65 years and older
All
Phase N/A

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Overview

The objectives of this study are to demonstrate the feasibility of implementing a deprescribing nudge intervention using pragmatic methods, confirm that outcomes can be feasibly measured and evaluated at scale in a subsequent embedded pragmatic clinical trial (ePCT), and explore representativeness of persons living with dementia and care partners identified.

Description

The PCP nudge will consist of: a 'pre-commitment' EHR nudge triggered when a PCP opens a patient encounter (i.e., prompt to first have a discussion and then later deprescribe) and a brief message within the in-basket prior to upcoming visits including information about their patient. The patient living with dementia (PLWD)/care partner nudge will include an electronic message delivered prior to upcoming visits (in their primary language recorded in the EHR) that includes a recommendation for the PLWD (and care partner, if available) to discuss medications with the PCP at the visit.

Eligibility

Primary care providers will be the primary unit of identification and randomization.

Primary care providers inclusion criteria:

  • Providers within Brigham and Women's Hospital primary care practices
  • Having prescribed at least one of the high-risk medications of interest

Eligible patients will be identified through this providers within the health care system.

Patient inclusion criteria:

  • At least 65 years of age
  • Prescribed at least 90 pills of one of the high-risk medications of interest in the last 180 days in the EHR system, which most guidelines consider chronic use, and have a diagnosis of dementia in the EHR.

Study details
    Alzheimer Disease
    Mild Cognitive Impairment
    Dementia

NCT06347172

Brigham and Women's Hospital

21 October 2025

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