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What Unmet Need for the Patients?A Focus on the Social Determinants of Health in Phase 1 Clinical Trials

What Unmet Need for the Patients?A Focus on the Social Determinants of Health in Phase 1 Clinical Trials

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18 years and older
All
Phase N/A

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Overview

An observational prospective study of patients enrolled and treated with experimental drugs in Phase I studies.

Description

The study focuses on defining the problem of geographical accessibility of patients to the Phase 1 facility of the European Institute of Oncology, based on an anonymized extraction of data from the enrolled patient database, to assess national territorial disparities in access to innovative experimental therapies, in relation to various socioeconomic determinants. Finally, information on relevant psychological factors for participation in clinical trials will also be collected.

Eligibility

Inclusion Criteria :

  • Patient with a histological or cytological diagnosis of solid or hematological tumor.
  • Age ≥ 18 years.
  • Patient enrolled in a phase 1 and early phase 2 study at our institution.
  • The patient has received at least 1 administration of the experimental drug under study in the early phase trial.

Exclusion Criteria :

  • Patients treated in phase 1 trials at other institutions, even if referred to our division or receiving standard therapies at IEO but outside of clinical trials, are not included.

Study details
    Solid Tumor

NCT06326242

European Institute of Oncology

21 October 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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