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Ultrasound Guided Rectus Sheath Block Versus Intrathecal Morphine for Postoperative Analgesia in Patients Undergoing Open Total Abdominal Hysterectomy

Ultrasound Guided Rectus Sheath Block Versus Intrathecal Morphine for Postoperative Analgesia in Patients Undergoing Open Total Abdominal Hysterectomy

Recruiting
18-65 years
Female
Phase N/A

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Overview

This study aims to compare the effectiveness and safety of ultrasound-guided rectus sheath block versus intrathecal morphine for postoperative analgesia in patients undergoing open total abdominal hysterectomy.

Description

Effective postoperative analgesia is crucial for enhancing recovery and patient satisfaction following major surgical procedures, such as total abdominal hysterectomy (TAH).

Rectus sheath block (RSB), an ultrasound-guided regional anesthesia technique, involves the injection of local anesthetic into the rectus sheath, providing analgesia to the anterior abdominal wall. RSB is used to block the sensory nerves of the anterior abdominal wall and thereby contributing to pain relief after lower abdominal surgeries.

Intrathecal morphine (ITM) provides a highly effective method of analgesia by delivering the medication directly into the cerebrospinal fluid (CSF).

Eligibility

Inclusion Criteria:

  • Age: 18 - 65 years old.
  • American Society of Anesthesiologists (ASA) physical status (I -II).
  • Patients undergoing open total abdominal hysterectomy.

Exclusion Criteria:

  • Hepatic, renal, or cardiac disease.
  • Any known allergy to local anesthetic.
  • Physical or mental conditions which may vague measuring postoperative pain following surgery.
  • History of chronic use of analgesic as nonsteroidal anti-inflammatory drugs (NSAIDs) or central nervous system (CNS) depressants as antiepileptic, and bleeding disorders.

Study details
    Ultrasound
    Rectus Sheath Block
    Intrathecal Morphine
    Postoperative Analgesia
    Total Abdominal Hysterectomy

NCT06837506

Ain Shams University

21 October 2025

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