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Influence of Food Texture on Appetite Control, Gastric Emptying, and Energy Expenditure

Influence of Food Texture on Appetite Control, Gastric Emptying, and Energy Expenditure

Recruiting
18-35 years
All
Phase N/A

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Overview

The aim of the study is to investigate the effect of liquid versus semi-solid meals on the regulation of energy balance in healthy young adults.The main questions it aims to answer are:

  • Does a protein-rich liquid meal result in less satiety and therefore higher ad libitum energy intake at the next meal than an isocaloric oatmeal with the same macronutrient ratio?
  • Is the consumption of a protein-rich liquid meal as a beverage in addition to an ad libitum oatmeal less compensated within the meal and at the next meal and provides thus a higher ad libitum energy intake than an isovolumetric noncaloric soft drink in addition to an ad libitum oatmeal?

Researchers will compare a protein-rich liquid meal to an isocaloric oatmeal with matched macronutrient composition to answer the first question. Researchers will compare a protein-rich liquid meal + oatmeal to a noncaloric softdrink (water with sucralose and flavoring) + oatmeal to answer the second question.

Participants will:

  • spend 4 intervention days in a metabolic chamber (whole room indirect calorimeter)
  • consume pre-definied preloads for breakfast and ad libitum lunch meals on 4 intervention days

Eligibility

Inclusion Criteria:

  • healthy males and females
  • Body Mass Index between 19-35 kg/m2
  • low to medium habitual physical activity
  • women with regular menstrual cycle (during intervention in follicular phase)

Exclusion Criteria:

  • smoking (cigarettes + cannabis)
  • chronic illnesses
  • regular intake of medication
  • Anemia and/or iron deficiency
  • food allergies / intolerances
  • vegans
  • regular high physical activity (exercise >1 hour/d)
  • current weight loss diet / weight loss of >5 kg in the last 3 months
  • restraint eaters (according to the German version of the 'Three-Factor-Eating-Questionnaire', Stunkard und Messick (1985))
  • active participation in another trial
  • pregnant / lactating women
  • persons incapable of giving informed legal consent

Study details
    Nutrition
    Healthy Male and Female Subjects

NCT06853249

University of Kiel

15 October 2025

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