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Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence Tomography

Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence Tomography

Recruiting
18 years and older
All
Phase N/A

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Overview

29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, including 7.7% to arterial catheters, with an influence on both morbility and mortality.

It is now accepted that biofilm as a role on bacterial development on inner surface of vascular devices but there is yet a lack of clinical relevant data documenting a causal relation between biofilm formation and bacteremias.

The investigators assume that a better structural and microbiological characterization of arterial catheter biofilm in ICU patients could help preventing bacteremias or have a more specific treatment when it appears.

Eligibility

Inclusion Criteria:

  • Patient or relative informed of the study and having declared their non-objection
  • Patient over 18 years old
  • Patient hospitalized in ICU with an arterial catheter

Exclusion Criteria:

  • Patient unable to express consent
  • Patient whose collection of the arterial catheter is impossible or for whom storage at 4°C is impossible
  • Patient with arterial catheter removed outside the usual procedure of the ICU
  • Patient admitted in ICU with an arterial catheter already in place

Study details
    Biofilms
    Arterial Catheterization
    Peripheral
    Bacteremia
    Tomography
    Optical Coherence

NCT06838598

Centre Hospitalier William Morey - Chalon sur Saône

15 October 2025

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