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Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy; A Randomized Controlled Clinical Trial

Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy; A Randomized Controlled Clinical Trial

Recruiting
18-39 years
Female
Phase N/A
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Overview

Laparoscopic myomectomy with temporary bilateral uterine artery occlusion or intramyometrial injection of diluted epinephrine will be important to reduce intraoperative bleeding, time of operation and hospitalization period after laparoscopic myomectomy.

Description

Laparoscopic myomectomy with temporary bilateral uterine artery occlusion or intramyometrial injection of diluted epinephrine will be important to reduce intraoperative bleeding, time of operation, and hospitalization period after laparoscopic myomectomy.

This will be the first study to investigate the efficacy of Laparoscopic myomectomy with temporary bilateral uterine artery occlusion or intramyometrial injection of diluted epinephrine in minimizing blood loss during Laparoscopic myomectomy at our university.

Can Laparoscopic myomectomy with temporary bilateral uterine artery occlusion or intramyometrial injection of diluted epinephrine give better outcomes regarding intraoperative bleeding when compared to traditional laparoscopic myomectomy?

Eligibility

Inclusion Criteria:

  1. Women aged from 18 to 39 years.
  2. Symptomatizing Women (heavy menstrual bleeding or subfertility).
  3. FIGO stage (3-7) by ultrasound.
  4. Only uterine corpus fibroid.
  5. Up to three fibroids by ultrasound.
  6. No previous hormonal treatment.

Exclusion Criteria:

  1. Patients with bleeding tendency.
  2. Patients who refuse to participate in the study or uncooperative patients.
  3. Current pregnancy.
  4. Any retroperitoneal surgery at pararectal space.
  5. More than one cesarean delivery.

Study details
    Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy

NCT06566352

Zagazig University

21 October 2025

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