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A Study on Pain After Breast Reconstruction

A Study on Pain After Breast Reconstruction

Recruiting
18 years and older
Female
Phase N/A

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Overview

The purpose of this study is to find out how common persistent postmastectomy pain (PPMP) is among people who have had a mastectomy and breast reconstruction surgery for their breast cancer. The study will also look at how effective regenerative peripheral nerve interface (RPNI) surgery is for reducing pain from neuropathic PPMP after breast reconstruction.

Eligibility

Inclusion Criteria:

  • Female
  • Age ≥18 years
  • History of mastectomy for breast cancer or genetic predisposition to breast cancer
  • History of breast reconstruction with implants and/or autologous tissue
  • At least 6 months of follow-up after reconstruction
  • Patient treated at MSK

Exclusion Criteria:

  • Exchange or revision surgery within 6 months
  • Active medical reason for pain (e.g., infectious, neoplastic, wound related)
  • Greater than 15 years post-reconstruction

Study details
    Mastectomy
    Mastectomy Patient
    Mastectomy and Breast Reconstruction
    Breast Reconstruction
    Breast Reconstruction After Mastectomy
    Postmastectomy Pain

NCT06627582

Memorial Sloan Kettering Cancer Center

15 October 2025

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