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Hi-Fatigue G Bone Cement Retrospective Study

Hi-Fatigue G Bone Cement Retrospective Study

Recruiting
18 years and older
All
Phase N/A

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Overview

The objective of this retrospective monocentric study is to collect survivorship and clinical data confirming safety, performance and clinical benefits for the Hi-Fatigue G Bone Cement.

The assessments will include:

  • Radiological analysis performed at different time points according to the standard of care of the hospital
  • Implant survivorship and safety based on removal of a study device
  • Patient reported outcome measures (PROMs)

Primary endpoint:

Assessment of radiolucent lines around the components (tibial, femoral, acetabular) at 5 years (in accordance with the hospital standard of care).

Secondary endpoints:

  • Evaluation of implant survivorship and safety by monitoring the frequency and incidence of adverse events. Relation of the events to implant, instrumentation and/or procedure should be specified.
  • Evaluation of PROMs
  • Obtain information regarding the cementing technique and handling of the cement, if available

Eligibility

Inclusion Criteria:

  • Subject qualified for cemented TKA or THA with a Zimmer Biomet implant
  • Subject is willing and able to give written informed consent for retrospective data collection and undergo interim and final evaluation (X-Ray & Scores completion)
  • Subject > 18 years old

Exclusion Criteria:

  • Muscle wasting
  • Neuromuscular compromise in the affected limb
  • Known hypersensitivity to any of the cement constituents
  • Subjects with severe renal failure
  • Bilateral interventions
  • Subject is a vulnerable subject (prisoner, mentally incompetent or unable to understand what participation to the study entails, known alcohol or drug abuser, anticipated to be non-compliant)

Study details
    Total Hip and Knee Arthroplasties

NCT06699134

Zimmer Biomet

15 October 2025

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