Overview
The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria. The main question it aims to answer is:
• How prevalent is cancer and precancerous tumors in the large intestines and rectum in patients with anaerobic bacteremia? Participants will be offered an examination using colon capsule endoscopy 4-8 weeks after discharge.
Eligibility
Inclusion Criteria:
- Older than 18 years
- Blood culture with growth of one or more of the following bacterial genera Bacteroides, Clostridium, Filifactor, Fusobacterium, Gemella, Granulicatella, Parvimonas, Peptostreptococcus, Prevotella, Solobacterium, Peptoniphilus, Ruminococcus, Finegoldia and Streptococcus.
- Able to provide oral and written informed consent
- Able to read and speak Danish
Exclusion Criteria:
- Prior colorectal cancer diagnosis
- History of stenosis of the gastrointestinal tract
- Previous treatment of inflammatory bowel disease
- Previous major surgery of the gastrointesinal tract (e.g. gastric bypass)
- Colostomy
- Pacemaker/ICD
- Pregnancy or breastfeeding
- Allergies to the bowel preparation regimen
- Severe kidney disease
- Focus of infection in skin and soft tissue or outside the truncus (e.g. decubitus, diabetic foot ulcer)
- Tumor in the colon or rectum at diagnostic imaging
- Discharge before result of blood culture
- Transfer to other hospital outside the region