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Symptom Burden and Health Related Quality of Life of Cancer Patients With Concurrent Heart Failure

Symptom Burden and Health Related Quality of Life of Cancer Patients With Concurrent Heart Failure

Recruiting
18 years and older
All
Phase N/A

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Overview

To describe and compare the symptom burden in cancer patients with concurrent diagnosis of heart failure (HFrEF compared to HFpEF).

Description

The investigators will conduct a symptom assessment at study enrollment on cancer participants with a concurrent diagnosis of HF (HFrEF and HFpEF) using the MD Anderson Symptom Inventory- Heart Failure (MDASI-HF) and PROMIS Instruments (Fatigue, Dyspnea, and Sleep Disturbance).

The investigators will also describe and compare the health-related quality of life using the European Organization for Research and Training Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and the measure of Quality of Life Short Form-12 (SF-12).

Eligibility

Inclusion Criteria:

  • Age 18 years and older
  • Individuals with a concurrent solid tumor cancer diagnosis
  • Not receiving active cancer treatment except for those on maintenance (i.e., Selective ER modulators (SERMs)[Tamoxifen], Aromatase inhibitors (Anastrozole, Letrozole, Exemestane), Ovarian suppression therapy (GnRH Agonists [Leuprolide], Androgen deprivation therapy for prostate cancer
  • Completed cancer treatment at least 3 months and up to 3 years before study enrollment.

Therapy

  • Able to read, speak and consent in English
  • Ability to understand and the willingness to sign a written informed consent document
  • Diagnosis of heart failure, confirmed by echocardiogram, MUGA, or cardiac catheterization
  • Internet access via smart phone, tablet, a computer, or another device with the capacity to 1) download the Fitbit App and 2) complete electronic study assessments via REDCap.

Exclusion Criteria:

  • Participants undergoing active cancer treatment.
  • Inability to provide consent in the medical record, such as cognitively impaired individuals.

Study details
    Heart Failure

NCT06656715

M.D. Anderson Cancer Center

15 October 2025

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