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Analgesic Efficacy of External Oblique Intercostal Block vs Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy

Analgesic Efficacy of External Oblique Intercostal Block vs Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy

Recruiting
18-65 years
All
Phase N/A

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Overview

To compare the efficacy of unilateral ultrasound-guided oblique subcostal transversus abdominis plane block with unilateral ultrasound-guided external oblique intercostal plane block in providing intraoperative and postoperative analgesia in cancer patients undergoing open nephrectomy.

Description

Open surgery remains one of the procedures used for those patients requiring partial or radical nephrectomy and is associated with a high incidence of severe immediate postoperative pain and chronic pain the months following surgery.

Regional anesthesia techniques are frequently recommended for pain control in open nephrectomy as they decrease the need for parenteral opioid and improve patient satisfaction.

Although abdominal wall blocks are known to decrease opioid requirements without causing epidural associated hypotension, their role in flank surgeries has been less well-established. The dermatomes that need to be covered in flank incision are T9 to T11.

Studies have confirmed that ultrasound-guided (USG) transversus abdominis plane (TAP) block is an effective method of analgesia for upper abdominal surgeries, lower abdominal surgeries and kidney transplantation with minimal side effects.

The external oblique intercostal (EOI) block is a novel method providing simple and effective somatic analgesia to the upper abdomen with minimal side effects. Other advantages include easy sonoanatomy (even in obese patients), being performed in the supine position, and no anticoagulation concern

Eligibility

Inclusion Criteria:

  • Age (18-65) year.
  • Both sexes.
  • American Society of Anesthesiologists (ASA) class II and III.
  • Cancer patients candidate for open nephrectomy .

Exclusion Criteria:

  • Patient refusal.
  • Skin lesions or infection at the site of proposed needle insertion.
  • Cognitive disorders.
  • History of psychiatric disorders or drug abuse.
  • Patients allergic to medication used.
  • ASA class IV.
  • Coagulopathy.
  • Body mass index (BMI) more than 35.

Study details
    Analgesic Efficacy
    External Oblique Intercostal Block
    Subcostal Transversus Abdominis Plane Block
    Open
    Nephrectomy

NCT06584695

Cairo University

15 October 2025

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