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Removable Titanium Clip Treatment for Acute Variceal Hemorrhage from the Gastric Fundus

Removable Titanium Clip Treatment for Acute Variceal Hemorrhage from the Gastric Fundus

Recruiting
18-75 years
All
Phase N/A

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Overview

Removable Titanium Clip Treatment for Acute Variceal Hemorrhage from the Gastric Fundus

Description

During the procedure, a removable titanium clip was used to block the bleeding vessels, enabling rapid hemostasis. Five days later, secondary preventive measures such as ECI or TIPS were performed. The titanium clip was removed during or after the procedure, avoiding its retention in the body, which could interfere with subsequent MRI examinations and related treatments. In situations where emergency ECI or other treatments are not feasible, this method can serve as a 'temporary bridge' for the treatment of acute gastric fundal variceal hemorrhage, potentially saving the patient's life.

Eligibility

Inclusion Criteria:

  1. The patient and their family agree to and sign the relevant informed consent form.
  2. Diagnosed with cirrhosis based on clinical manifestations, laboratory tests, imaging findings, or pathological examinations.
  3. History of symptoms related to variceal upper gastrointestinal bleeding, such as hematemesis, melena, or rectal bleeding.
  4. Patients confirmed by endoscopy to have bleeding from ruptured gastric varices.
  5. Patients who are hemodynamically stable before or after initial fluid resuscitation.
  6. Aged 18 to 75 years.

Exclusion Criteria:

  1. Those with concomitant bleeding from ruptured esophageal varices.
  2. A history of gastrointestinal-related surgical procedures.
  3. Individuals with altered consciousness who are difficult to treat.
  4. Those with concomitant malignant tumors.
  5. Individuals with serious diseases involving the heart, brain, lungs, or kidneys.
  6. Pregnant and breastfeeding women.
  7. Those with contraindications to relevant treatments.

Study details
    Gastric Variceal Bleeding

NCT06736314

Shupei Li

15 October 2025

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