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Local Tranexamic Acid During Vaginal Hysteractomy to Reduce Blood Loss

Local Tranexamic Acid During Vaginal Hysteractomy to Reduce Blood Loss

Recruiting
20-90 years
Female
Phase N/A
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Overview

Assessing the efficiency of Prophylactic use of local tranexamic acid during vaginal hysterectomy to reduce blood loss during operation

Description

This randomized control trial will investigate whether local tranexamic acid is efficient for decreasing bleeding during vaginal hysterectomy.

The investigators will randomize local placebo (saline) vs. local 1 gr tranexamic acid; local 1gr tranexamic acid diluted in 10 ml saline and local 10 ml saline at the beginning of surgery.

Eligibility

Inclusion Criteria:

  • 20-90 years old female patients going through vaginal hysterctomy

Exclusion Criteria:

  • massive bleeding during operation due to major vessles injury
  • known coagulopathies
  • sensitivity to tranexamic acid
  • medical need in tranexamic acid administration during operation due to bleeding

Study details
    Blood Loss

NCT04760301

Meir Medical Center

15 October 2025

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