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Memory Deterioration in Alzheimer Disease

Memory Deterioration in Alzheimer Disease

Recruiting
55 years and older
All
Phase N/A

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Overview

Semantic AD

Eligibility

Inclusion Criteria:

  • Confirmed diagnosis based on current ICD criteria for AD or MCI .
  • >55years.
  • Norwegian native speaker
  • Lives at home and not in a health institution

Exclusion Criteria:

  • Patients with severe cognitive impairment that prevents assessment with the selected modalities (planned cut-off: CDR > 2).
  • Presence of brain tumors.
  • History of traumatic brain injury.
  • History of cranial surgery.
  • Contraindications to the selected imaging modalities (e.g., 7T MRI or EEG).
  • Diagnosis of other neurodegenerative diseases such as Parkinson's disease or ALS.

    7T MRI contraindications:

  • Large tattoos close to the head region, permanent makeup or unremoveable piercings
  • Certain models of pacemakers (if pacemaker implantet, MRI physicist at 7T-lab will be conferred)
  • Implantet metal in body (clips, stents, prothesis, skrews, plates, teeth etc.)

Study details
    Alzheimer Disease
    Neurodegenerative Diseases
    Magnetic Resonance Imaging
    Memory Impairment

NCT07118137

Norwegian University of Science and Technology

15 October 2025

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