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Neuromodulation With Spinal Stimulation Methods

Neuromodulation With Spinal Stimulation Methods

Recruiting
18-65 years
All
Phase N/A

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Overview

This is a pilot research study to test the protocols needed for transcutaneous spinal electrical stimulation in persons living with spinal cord injury (SCI). Up to 24 participants will be enrolled. A variety of stimulation parameters and outcome measures will be assessed.

Description

Purpose of this project

Spinal cord stimulation has the potential to improve motor function recovery after spinal cord injury. Commonly used approaches include low-intensity, direct current (DC) stimulation applied across multiple segments, electrical transcutaneous (ETC) stimulation, and magnetic transcutaneous stimulation (MTC).

Objective: to evaluate and compare the voluntary and reflexive motor performance in the same subjects, including people with and without spinal cord injury, after non-invasive spinal cord stimulation interventions. Comparing two different interventions applied in different experimental sessions and the respective sham stimulation is the goal of this study.

corticospinal and spinal motor pathways in paraplegics and in non-injured humans will be tested.

Eligibility

Inclusion Criteria:

  • spinal cord injury C4 to L4
  • ability to understand and follow directions

Exclusion Criteria:

  • history of seizures, head injury, concussion, unexplained loss of consciousness or if they lived with an implanted cochlear stimulator, brain/neurostimulator, cardiac pacemaker, medication infusion device or live with metal implants in their body or if they are pregnant.

Study details
    Spinal Cord Injuries
    Spinal Cord Injury at C5-C7 Level
    Paraplegia
    Spinal
    Paraplegia
    Incomplete

NCT06272279

University of Manitoba

15 October 2025

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