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Predictive Performance of a Generative Model for Corneal Tomography After ICL Implantation

Predictive Performance of a Generative Model for Corneal Tomography After ICL Implantation

Recruiting
18-45 years
All
Phase N/A

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Overview

To evaluate the efficacy of a corneal tomography Imaging model in predicting postoperative vault based on preoperative corneal topography in Implantable Collamer Lens (ICL) surgery.

Description

Accurate vault prediction is crucial for Implantable Collamer Lens (ICL) surgery safety and efficacy. Current methods using preoperative biometrics and regression formulas show limited accuracy due to parameter variability and incomplete utilization of corneal topography data. To address this, we developed a deep learning model that predicts postoperative vault while generating anterior chamber morphology images from preoperative data, enabling personalized surgical planning.

Eligibility

Inclusion Criteria:(1) stable myopia (≤0.50D/year change for 2 years), (2) ACD ≥2.80mm, (3) intact corneal endothelium (≥2000 cells/mm²), and (4) no confounding ocular/systemic conditions.

Exclusion Criteria:(1) glaucoma-spectrum disorders or retinal vasculopathies, (2) prior corneal/intraocular surgery, (3) compromised corneal endothelium, (4) uncontrolled systemic diseases, and (5) pregnancy/lactation.

Study details
    ICL
    Vault
    Deep Learning
    AI (Artificial Intelligence)

NCT07146737

Second Affiliated Hospital of Nanchang University

15 October 2025

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