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Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery

Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery

Recruiting
22 years and older
All
Phase N/A

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Overview

To review how patients report using a hyaluronate crosslinked canalicular gel placed before cataract surgery

Description

Prospective, single-site, single-arm study enrolling 60 patients who have elected advanced IOL implantation at the time of cataract surgery and have a diagnosis of dry eye disease. The study will consist of 5 study visits, over a 3-5 month time period. Patients will receive bilateral lacrimal occlusion of crosslinked hyaluronate canalicular gel pre-operatively.

Eligibility

Inclusion Criteria:

  • Be willing and able to understand and sign the informed consent form (ICF)
  • Men or non-pregnant women age 22 or older
  • Clear intraocular media other than cataract
  • Diagnosis of dry eye disease (OSDI score ≥ 13)
  • Non-invasive Tear break up time ≤ 10 seconds in at least one eye
  • Willing and able to comply with all study related visits and procedures
  • In the opinion of the investigator, patients who are appropriate for advanced technology lens implants

Exclusion Criteria:

  • History of punctal cautery
  • Lacrimal anatomy (e.g., nasolacrimal duct obstruction) that per investigator suggests that the patient would not be a good candidate for lacrimal occlusion or patients for whom lacrimal occlusion would increase risk

Study details
    Dry Eye Disease (DED)

NCT07155057

Vance Thompson Vision

15 October 2025

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