Image

Radiographic and Histomorphometric Assessment for Maxillary Sinus Floor Elevation and Augmentation Using A Mixture of 1:1 Autogenous Bone With Deproteinized Bovine Bone Particulate Versus Deproteinized Bovine Bone Particulate

Radiographic and Histomorphometric Assessment for Maxillary Sinus Floor Elevation and Augmentation Using A Mixture of 1:1 Autogenous Bone With Deproteinized Bovine Bone Particulate Versus Deproteinized Bovine Bone Particulate

Recruiting
30 years and older
All
Phase N/A

Powered by AI

Overview

two group of patients with atrophied posterior maxilla that need implant/s placement. one group will be subjected to maxillary sinus floor elevation using 1:1 mixture of autogenous bone and deproteinized bovine bone particulate while the other will be subjected to maxillary sinus floor elevation using deproteinized bovine bone particulate alone.

Description

• Preoperative imaging using CBCT will be performed to assess the anatomy of the maxillary sinus, including the presence of septa, the thickness of the sinus membrane, and the quality and quantity of bone available for grafting and to exlude the presence of any pathosis.

Phase 1 (concerning maxillary sinus floor elevation and Graft placement):

  • All surgical procedures will be performed by a single experienced oral surgeon to minimize variability.
  • All patients in the two groups would be operated under Local anaesthesia, a full-thickness mucoperiosteal flap originating from the midcrestal area or slightly toward the palate side would be opened.
  • A lateral window will be created in the maxillary bone using, The window should be large enough to allow for adequate access to the sinus membrane.
  • The Schneiderian membrane will be carefully elevated using a sinus elevator or similar instrument.
  • Once the membrane is elevated, Depending on the allocation, graft material will be placed into the sinus cavity either using A mixture of 1:1 Autogenous Bone with Deproteinized Bovine Bone Particulate Versus Deproteinized Bovine Bone Particulate.
  • a collagen membrane will be placed over the graft material. The membrane should be trimmed to fit the dimensions of the lateral window and secured in place using resorbable sutures or tacks if necessary.
  • The mucoperiosteal flap will be repositioned and secured using sutures.

Phase 2 (delayed implant placement and core biopsy harvesting 6 Months Postoperative):

  • A full thickness mucoperiosteal flap originating from the mid-crestal area or slightly towards palate side would be opened for both groups.
  • A core biopsy would be harvested from both groups using trephine burs from the site of implant placement prior to drilling, to be sent to the Lab for Histological assessment.

The mucoperiosteal flap will be repositioned and secured using sutures

Eligibility

Inclusion Criteria:

  • • Patients of both genders requiring implants placement in atrophied posterior maxilla with residual bone height less than 5mm .
    • Patients of age older than 30 years old.
    • Patients with adequate Inter-arch space.
    • Patients who were willing and fully capable to comply with the study protocol.

Exclusion Criteria:

  • • Patients suffering from any sinus pathosis
    • Heavy smokers (> than 10 cigarettes a day)
    • Patients with parafunctional habits
    • Patients with uncontrolled systemic diseases.
    • Patients with poor oral hygiene
    • Patients with mental instabilities or psychic patients

Study details
    Maxillary Sinus Lifting

NCT07177495

Cairo University

15 October 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.