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General Anesthesia Versus Spinal Anesthesia With Local Anesthetic Infiltration for Buccal Mucosal Graft in Urethroplasty

General Anesthesia Versus Spinal Anesthesia With Local Anesthetic Infiltration for Buccal Mucosal Graft in Urethroplasty

Recruiting
21 years and older
Male
Phase N/A

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Overview

This study aims to compare general anesthesia and spinal anesthesia with local anesthetic infiltration for buccal mucosal graft (BMG) in urethroplasty.

Description

Urethroplasty is a surgical procedure aimed at reconstructing the urethra and is considered the standard treatment for bulbar urethral strictures, with different types of tissues used as either grafts or flaps, affecting approximately 300 per 100,000 males.

Postoperative pain following urethroplasty with buccal mucosal graft (BMG) is primarily related to the oral graft harvest site.

General Anesthesia provides a state of complete unconsciousness, ensuring that patients are free from pain and awareness during the surgery. It can be beneficial in complex cases or when extended manipulation is required, allowing for muscle relaxation and controlled ventilation.

On the other hand, spinal anesthesia involves the injection of anesthesia into the cerebrospinal fluid, resulting in targeted numbness in the lower body. This technique can be advantageous for its fast, simple, cost-effective method, rapid onset, lower risk of systemic complications, and preservation of airway reflexes.

Eligibility

Inclusion Criteria:

  • Male patient age ≥ 21 years.
  • American Society of Anesthesiologists (ASA) classification I-II.
  • Patient scheduled for urethroplasty.

Exclusion Criteria:

  • Patients who are taking analgesics for chronic illness or have a history of substance abuse.
  • Patients who are unable to describe their postoperative pain (e.g., neuropsychiatric disorder).
  • Patients with known local anesthetics and opioid allergy.
  • Patients with infection at the site of the needle puncture.

Study details
    General Anesthesia
    Spinal Anesthesia
    Local Anesthetic Infiltration
    Buccal Mucosal Graft
    Urethroplasty

NCT07074730

Tanta University

15 October 2025

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