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Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer

Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer

Recruiting
18 years and older
All
Phase N/A

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Overview

The primary objective of this observational study is to investigate the incidence of Post Operative Delirium (POD) after gastroesophageal cancer surgery. Secondary objectives are to investigate the relationship between POD, preoperative depression, frailty, quality of life, malnutrition and sarcopenia.

Participants identified with POD will be asked (at the routine follow-up meeting after surgery) to participate in an qualitative interview, in order to understand the participant's experience of postoperative delirium.

The main objective aims to answer:

What is the incidence of POD after gastroesophageal cancer surgery.

Eligibility

Inclusion Criteria:

  • Patients diagnosed with esophageal or gastric cancer, treated with (or without) chemotherapy and surgery.
  • Age ≥18 at the time for inclusion.
  • Participate on a voluntary basis and can (for any reason) end its participation during the study.
  • Capable of giving informed consent.

Exclusion Criteria:

  • Patients with preoperative cognitive dysfunction such as dementia.
  • Patients who are inoperable due to metastases.
  • Patients unable to communicate due to severely impaired hearing and/or - seeing.
  • Patients with ongoing drug and/or alcohol abuse.
  • Patients who cannot give informed consent.

Study details
    Gastroesophageal Cancer (GC)
    Postoperative Delirium (POD)
    Quality of Life (QOL)
    Frailty
    Malnutrition
    Sarcopenia
    Chemobrain
    Chemotherapy
    Depression

NCT06687291

Karolinska Institutet

15 October 2025

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