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Initial Pilot Study to Evaluate the Safety and Temporary Symptom Improvement Efficacy of CKD-981

Initial Pilot Study to Evaluate the Safety and Temporary Symptom Improvement Efficacy of CKD-981

Recruiting
40-80 years
All
Phase 2

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Overview

The purpose of this study is to prove that the temporary symptom improvement effect on knee osteoarthritis using CKD-981

Description

The aim of this pilot study is to evaluate the efficacy and safety of CKD-981 in patients with mild to moderate degenerative knee osteoarthritis who have been experiencing pain more than 8 weeks

Eligibility

Inclusion Criteria:

  • Patients between 40 years and 80 years old
  • Patients who have experiencing knee pain more than 8 weeks
  • VAS more than 40 mm
  • Kellgren and Lawrence grade 2 and 3 in X' ray knee joint

Exclusion Criteria:

  • Previous knee surgery in affected side
  • Patients with Rheumatoid arthritis, connective tissue disease, Paget's disease
  • Infection of knee joint
  • BMI more than 35kg/m2

Study details
    Knee Osteoarthritis

NCT06954766

Chong Kun Dang Pharmaceutical

15 October 2025

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