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Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use

Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use

Recruiting
18 years and older
Female
Phase 4

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Overview

The purpose of this study is to determine whether an injection of a local anesthetic (Bupivacaine with epinephrine) in the vaginal cuff prior to closure would result in less immediate postoperative pain medication and increase patient comfort/satisfaction.

Eligibility

Inclusion Criteria:

  • Patients 18 years and older requiring total laparoscopic hysterectomy with or without bilateral salpingo-oophorectomy for benign conditions
  • Presence of malignancy

Exclusion Criteria:

  • Conversion to laparotomy
    • Previous multiple abdominal and/or pelvic surgeries
    • Significant medical comorbidities or cardiac history
    • Poor initial Aldrete score4 (<10)
    • Significant pre-op pain medication use
    • Contraindication to any medication that would be used in the study (Bupivacaine, epinephrine, tramadol or oxycodone)

Study details
    Hysterectomy
    Post Operative Analgesia

NCT06719180

MediSys Health Network

15 October 2025

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